6/2/2023 0 Comments Fractured by Mason SabreThere is a strong need for the development and validation of new prediction models based on Asian data for Asian populations. The calibration of existing models is poor, particularly in Asian populations. The ability of these models to discriminate between those individuals who will and will not have a fracture (i.e., area under the receiver operating characteristic curve ) is generally acceptable-to-good (AUC, 0.6 to 0.8), and is highly variable between populations. These models use different risk profiles to estimate the probability of fracture over 5- and 10-year period. Over the past 10 years, a number of predictive models (e.g., FRAX, Garvan Fracture Risk Calculator, and Qfracture) have been developed for individualized assessment of fracture risk. The risk of fracture is determined by multiple risk factors, and their effects may be interactional. Fragility fracture is a serious clinical event, because it is associated with increased risk of mortality and reduced quality of life.
0 Comments
Leave a Reply. |